Whole Body Exposure Chambers TPHRL has three separate systems for tobacco smoke consisting of 8 whole body exposure chambers. Each system has a smoke generating machine and either 2 or 3 Hinners-type chambers connected to a carbon monoxide analyzer. In addition, a diffusion flame system is available to serve as a surrogate to diesel engine (combustion) exposure. Nose-Only Exposure System TPHRL has a nose-only exposure system for aerosolized delivery of gases, vapors, and particles to multiple ports. This system has been successfully used for the study of electronic-cigarettes and is adaptable for other types of nose-only exposures. Biochemistry Lab and Tissue Processing A basic biochemistry lab is available with multiple fume hoods and equipment and bench space for analyses to be done. Room is dedicated to tissue processing, slicing, and embedding as well. Surgical Suite A surgical suite is located in the facility for small animal minor surgical procedures, such as oropharyngeal aspiration, intranasal administration of compounds, and pulmonary testing.