My research focus on the function of receptors for xenobiotics and inflammatory signaling to understand molecular mechanisms of the development of chronic inflammatory diseases promoted by environmental toxicants. We investigate how the innate immune system is affected after exposure to environmental pollutants during and after differentiation. Autoimmune diseases, including allergy, asthma, and even cancer, are based on or associated with non-functional or deregulated immune responses and remain the leading cause of death worldwide despite improved prognosis and aetiological understanding.